The best Treatment for Actinic Keratosis is prevention, and decrease exposure to the sun plays a very big role in determining the health of the skin. The use of different home remedies and Actinic Keratosis Natural Treatment can provide relief from the problem. Some Home Remedies for Actinic Keratosis you can try to help get rid of the cosmetic aspect of the spots: the rough, scaly, discolored patches of skin.