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Top Physiotherapy Exercises for The Relief of Sciatic Pain Here are a few of the more commonly prescribed exercises to help relieve sciatica pain: Understanding Sciatica: What Causes the Pain? Sciatica occurs most often due to compression or irritation of the sciatic nerve. Common reasons for compression or irritation include herniated discs, spinal stenosis, piriformis syndrome, or degenerative disc diseases. The pain can vary in intensity, but it may get worse when sitting for prolonged periods, coughing, sneezing, or with other sudden movements.