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The 20 mg tablets are brown, round, convex tablets marked OC on one side and 20 on the other. OxyContin OC 20 mg is helping moderate to severe pain and directly affects the brain. Grapefruit can increase the chance of side effects with this medicine. watering eyes, runny nose, nausea, diarrhea, sweating, muscle aches, or sudden changes in behavior are some symptoms then you can tell your doctor.